Colony stimulating factors: molecular and cellular biology
نویسندگان
چکیده
منابع مشابه
The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors.
Rapid progress has occurred recently in characterizing the molecular nature of the specific glycoprotein colony-stimulating factors (CSFs) controlling the proliferation; and some functional activities of granulocytes and monocyte-macrophages. All four known murine CSFs have been purified, and cDNAs for two have been cloned and expressed by mammalian and bacterial cells. Similarly, three human C...
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Macrophages or mononuclear phagocytes are heterogeneous populations present throughout the body which can adapt quite dramatically to the surrounding milieu, both in the steady state and during immune/inflammatory responses. To assist in our understanding of this diversity, they have been classified into polarization or “activation” states, termed M1 and M2, respectively. This in vitro classifi...
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The colony-stimulating factors (CSFs) form a family of hemopoietic growth factors controlling the survival, proliferation and differentiation of hemopoietic progenitor cells as well as the functional activities of the mature cells in the tissues [1]. In the mouse, four distinct CSFs controlling granulocyte and macrophage production have been identified, purified and, in two cases, molecularly c...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1990
ISSN: 0014-5793
DOI: 10.1016/0014-5793(90)80422-f